A WELL-ESTABLISHED DOSING SCHEDULE

SPINRAZA goes directly where it’s needed, targeting cells within the central nervous system (CNS)

Lauren
age 20

Later-onset (Type 3) SMA
treated with SPINRAZA

Patient taking SPINRAZA on the train

The SPINRAZA dosing schedule is designed to provide an appropriate level of medication that is maintained between each dose.

The SPINRAZA dosing regimen consists of initial loading doses followed by less frequent maintenance doses. Speak to your healthcare provider (HCP) for additional information about the dosing schedule and treatment procedure.

The recommended dosage of SPINRAZA is 12 mg (5 mL) per administration.

What to expect

SPINRAZA is given as an injection into the cerebrospinal fluid (the fluid in the spine) via a medical procedure called intrathecal injection, a well-established route of medication delivery used to target the CNS.

The intrathecal procedure is performed in a healthcare setting by or under the direction of experienced HCPs.


Find a treatment center

See pediatric and/or adult facilities that might be able to administer SPINRAZA.

IMPORTANT SAFETY INFORMATION

Increased risk of bleeding complications has been observed after administration of similar medicines. Your healthcare provider should perform blood tests before you start treatment with SPINRAZA and before each dose to monitor for signs of these risks. Seek medical attention if unexpected bleeding occurs.

Increased risk of kidney damage, including potentially fatal acute inflammation of the kidney, has been observed after administration of similar medicines. Your healthcare provider should perform urine testing before you start treatment with SPINRAZA and before each dose to monitor for signs of this risk.

The most common side effects of SPINRAZA include lower respiratory infection, fever, constipation, headache, vomiting, back pain, and post-lumbar puncture syndrome.

These are not all of the possible side effects of SPINRAZA. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking SPINRAZA, tell your healthcare provider if you are pregnant or plan to become pregnant.

Please see full Prescribing Information.

As a courtesy, our full Prescribing Information is also available en Español. For prescribing decisions, please refer to official approved labeling.

This information is not intended to replace discussions with your healthcare provider.


INDICATION

SPINRAZA is a prescription medicine used to treat spinal muscular atrophy (SMA) in pediatric and adult patients.